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晚期肾衰与长期使用止痛药合剂的流行病学临床资料较少,且有争论。本文介绍长期服用止痛药使肾衰的危险性增高,作者分析了1984～1986年。921例长期接受血液透析的晚期肾衰病人以前服用止痛药的资料,对照组为年龄与性别相匹配的门诊病人,长期应用止痛药的标准为每月使用止痛药,包括片剂,水剂或栓剂≥1 5剂,并持续一年以上者。结果表明,长期使用止痛合剂者,发生肾衰的相对危险性(RR)显著增高,RR的增高与止痛药物的剂量和持续用药时间有关。每月止痛药合剂≤60剂
There is little epidemiological clinical data on late renal failure and long-term use of analgesics, and there are controversies. This article describes the long-term use of painkillers to increase the risk of renal failure, the author analyzed from 1984 to 1986. 921 patients with advanced renal failure who received long-term hemodialysis had previously received data on painkillers in the control group as age-and-gender outpatients with long-term use of painkillers as monthly analgesics including tablets, Suppository ≥ 150, and continued for more than one year. The results showed that long-term use of painkillers, the relative risk of renal failure (RR) was significantly increased RR increased with the analgesic dose and duration of medication related. Monthly analgesic mixture ≤ 60 agent