临床资料表明性激素能够影响心血管功能。比如,目前认为雌激素能够预防某些心血管疾患。这种保护性机制的生物化学基础尚未搞清。过去研究雌二醇受体时曾将心肌做为非靶组织的对照组织。近来,对大鼠心脏进行自动放射照像方法的研究发现氚标记的雌二醇集中在大鼠心房各部位的心肌细胞核中。本文作者研究的目的是寻找人类心脏组织中的雌激素和孕酮受体。孕酮受体的发现是雌激素 Clinical data show that sex hormones can affect cardiovascular function. For example, estrogen is currently thought to prevent certain cardiovascular conditions. The biochemical basis of this protective mechanism remains unclear. In the past, estradiol receptors were used as a control tissue for non-target tissues. Recently, a study of automated radiographic methods in rat hearts found that tritiated estradiol was concentrated in the myocardial nuclei of various parts of the rat atria. The purpose of this study is to find estrogen and progesterone receptors in human heart tissue. The discovery of progesterone receptors is estrogen