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目的探讨液基细胞学检查(TCT)、阴道镜下宫颈活检对宫颈上皮内瘤变(CIN)的诊断价值。方法对1 358例妇科门诊患者行TCT检查,对85例阳性患者行电子阴道镜检查及镜下活组织病理检查。结果TCT检查阳性的85例(占6.26%)中不典型鳞状上皮细胞(ASCUS)27例(占1.99%),低度鳞状上皮内病变(LSL)49例(占3.61%),高度鳞状上皮内病变(HSL)9例(占0.60%)。CIN的电子阴道镜图像主要是不同程度的醋酸白色上皮、血管异常改变和碘阴性染色,不同程度的醋酸白色上皮在大部分CIN患者中被发现,病理学诊断CINⅠ41例,CINⅡ21例,CINⅢ6例,慢性宫颈炎15例,浸润癌(SCC)2例。结论应用TCT联合电子阴道镜检查及镜下活组织检查,能提高CIN的早期诊断率,对防治宫颈癌有积极作用。
Objective To investigate the diagnostic value of liquid-based cytology (TCT) and colposcopic biopsy for cervical intraepithelial neoplasia (CIN). Methods A total of 1 358 gynecological outpatients underwent TCT examination and 85 cases of positive patients underwent colposcopy and microscopic biopsy. Results There were 27 cases (1.99%) of atypical squamous cells (ASCUS), 49 cases (3.61%) of low grade squamous intraepithelial lesion (LSL) in 85 cases (6.26% Nine cases (0.60%) had intraepithelial lesion (HSL). CIN electron colposcopy images are mainly varying degrees of acetic acid white epithelium, vascular abnormalities and iodine-negative staining, varying degrees of acetic acid white epithelium was found in most patients with CIN, pathological diagnosis of CINⅠ41 cases, CINⅡ21 cases, CINⅢ6 cases, Chronic cervicitis in 15 cases, invasive carcinoma (SCC) in 2 cases. Conclusion TCT combined with electronic colposcopy and microscopic biopsy can improve the early diagnosis rate of CIN and have a positive effect on the prevention and treatment of cervical cancer.