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目的:探讨浙江地区2型糖尿病发病的潜在危险因素,以便科学有效地预防糖尿病发生。方法:通过对浙江省人民医院18岁～83岁的642例2型糖尿病住院患者采用非条件Logistic回归方法分析糖尿病的危险因素。结果:单因素分析显示腰臀围比≥1.3、BMI≥23.8 kg/m2、吸烟史、饮酒史、家族史、高血清总胆固醇(TC)、高血清甘油三酯(TG)、高水平低密度脂蛋白(LDL)、高水平空腹胰岛素、高血尿酸和高血压可能是2型糖尿病的危险因素。经多因素非条件Lo-gistic回归分析显示腰臀围比(OR=2.203),甘油三酯(OR=1.223),低密度脂蛋白(OR=1.273),高血压(OR=1.672),家族史(OR=2.570)是2型糖尿病的主要危险因素。结论:本研究显示肥胖、高血脂、高血压和家族史是2型糖尿病的独立危险因素。
Objective: To explore the potential risk factors of type 2 diabetes in Zhejiang province in order to prevent diabetes from occurring scientifically and effectively. Methods: Non-conditional Logistic regression was used to analyze the risk factors of diabetes in 642 patients with type 2 diabetes from 18 to 83 years old in Zhejiang Provincial People’s Hospital. Results: Univariate analysis showed that waist-hip ratio≥1.3, BMI≥23.8 kg / m2, smoking history, alcohol consumption history, family history, serum total cholesterol (TC), high serum triglyceride (TG), high level of low density Lipoprotein (LDL), high levels of fasting insulin, hyperuricemia and hypertension may be risk factors for type 2 diabetes. The multivariate non-conditional Lo-gistic regression analysis showed that the ratio of waist to hip (OR = 2.203), triglyceride (OR = 1.223), low density lipoprotein (OR = 1.273), hypertension (OR = 2.570) is a major risk factor for type 2 diabetes. Conclusion: This study shows that obesity, hyperlipidemia, hypertension and family history are independent risk factors for type 2 diabetes.