一、引言 近年来,有关报导cAMP的文献既多且广,是当前分子生物学研究的重要内容之一。许多研究表明,cAMP与高血压、气喘、肿瘤、牛皮癣、糖尿病和肥胖症等皆有密切关系。有人建议以cAMP为基础发展药物,并将药物按cAMP系统进行分类。为此摸索一个简便有效的合成cAMP的方法日显重要。 I. INTRODUCTION In recent years, the literature about cAMP is both extensive and broad, which is one of the important contents of current molecular biology research. Many studies show that cAMP is closely related to hypertension, asthma, cancer, psoriasis, diabetes and obesity. It has been suggested to develop drugs based on cAMP and classify the drugs according to the cAMP system. To explore a simple and effective method for the synthesis of cAMP becomes increasingly important.