研究者发现,有些抗体既能预防葡萄球菌感染,又能预防大肠杆菌感染,因为这两种细菌在其细胞壁中使用相同的多糖相互结合。由于其他几种致病菌也使用相同的多糖,因此,这一发现为单一疫苗预防各种细菌带来了希望。这一发现的本质涉及细胞间黏附的外多糖聚 N-乙酰葡糖胺(PNAG)。PNAG 是一种有希望的葡萄球 The researchers found that some antibodies prevent both staphylococcal infections and E. coli infections because both bacteria use the same polysaccharide in their cell walls to bind to each other. Because several other pathogens also use the same polysaccharide, this finding offers the promise of a single vaccine to prevent various bacteria. The essence of this discovery relates to the extracellular polysaccharide poly-N-acetylglucosamine (PNAG) that is attached to the cell. PNAG is a promising grape ball