细叶小檗(Berberis poiretii Schn.)有效成分Ⅳ-3结晶是中国科学院林业土壤研究所从细叶小檗根中提取的一种水难溶性生物碱。系黄色结晶,经高分辨质谱分析,m/e 为355.1133,分子式为 C_(20)H_(17)NO_4,初步确定为阿朴菲(aporphine)型生物碱。我室用该药做了心血管方面的药理实验。实验结果表明,当给小鼠腹腔注射Ⅳ-3结晶0.2mg/10g 体重时,有明显的抗减压缺氧作用,给药组的平均生存时间为8.49± Berberis poiretii Schn. active ingredient IV-3 crystal is a kind of insoluble alkaloid extracted from the root of Bletilla striata. The yellow crystals were analyzed by high resolution mass spectrometry. The m/e was 355.1133 and the molecular formula was C_(20)H_(17)NO_4. The aporphyrine alkaloid was initially identified. My department used this medicine to do cardiovascular pharmacology experiments. The experimental results showed that when the mice were intraperitoneally injected with IV-3 crystal 0.2mg/10g body weight, there was significant anti-hypobaric hypoxia effect, and the average survival time of the administration group was 8.49±