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摘要目的研究多光谱光声层析成像(MSOT)能否显示体内毫米级直径的肿瘤内感兴趣外源性因子的不均匀分布与血管特征。材料与方法研究涉及动物的部分由上巴伐利亚政府批准。应用实验MSOT设备行小鼠皮下组织成像,每秒生成10幅横断面影像,层内分辨率约为150μm。为研究动态对比增强成像
Abstract Objective To investigate whether multispectral photoacoustic tomography (MSOT) can show the inhomogeneous distribution and vascular characteristics of tumor-associated exogenous factors within the millimeter-diameter tumors in vivo. Materials and methods Part of the research involving animals was approved by the Upper Bavarian government. Using the experimental MSOT device, mice were subcutaneously imaged with 10 cross-sectional images per second with an intra-layer resolution of approximately 150 μm. To study dynamic contrast enhancement imaging