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链褐霉素(原名72-2583)是上海医药工业研究院在1972年于我国广东省土壤中找到的一株放线菌所产生的抗肿瘤抗菌素。从产生菌的生长和生理生化特性,以及链褐霉素的理化性质、药理、毒理试验证明,与国外报道的链霉黑素基本一致。链霉黑素(Streptonigrin)是美国于1958年发现的,法国于同年找到绛色霉素(Rufochro-momycin),苏联于1963年发表了褐霉素(Bruneomycin),后经证明三者系相同物质。美国
Streptomycin (formerly 72-2583) is an antitumor antibiotic produced by an actinomycete found by the Shanghai Institute of Pharmaceutical Industry in the soil of Guangdong Province in China in 1972. From the growth of bacteria and physiological and biochemical characteristics, as well as the physical and chemical properties of streptomycin, pharmacological and toxicological tests showed that streptavidin reported abroad is basically the same. Streptonigrin was discovered in the United States in 1958. France found Rufochro-momycin in the same year. The Soviet Union issued Bruneomycin in 1963, and the latter proved to be the same substance . United States