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我们检测了９００多例男性不育症患者的血清、精浆抗精子抗体（ＡｓＡｂ）和精液各项指标，对其中２１３例ＡｓＡｂ阳性患者的精液有关参数与ＡｓＡｂ的关系进行了分析，并与生育男性组作了比较。结果表明，ＡｓＡｂ阳性患者的精子密度、精子活率、精子顶体完整率、精浆免疫抑制物（ＳＰＩＭ）及α－糖苷酶均明显低于生育组（Ｐ＜０．０１），不育男性ＡｓＡｂ阳性组ＳＰＩＭ阳性率也明显高于ＡｓＡｂ阴性组（Ｐ＜０．０１）。此外，血清与精浆ＡｓＡｂ同为阳性组的精子活率明显低于单纯血清或精浆ＡｓＡｂ阳性组（Ｐ＜０．０１）。
We examined sera, seminal plasma antisperm antibody (AsAb), and semen levels in more than 900 male infertility patients and analyzed the relationship between semen parameters and AsAb in 213 AsAb-positive patients and compared them with fertility Men were compared. The results showed that sperm motility, sperm motility, sperm acrosome integrity, SPIM and a-glucosidase were significantly lower in AsAb-positive patients than in fertility group (P <0.01) The positive rate of SPIM in AsAb positive group was also significantly higher than that in AsAb negative group (P <0.01). In addition, the sperm motility of AsAb-positive sera was significantly lower than that of sera or AsAb-positive seminal plasma (P <0.01).