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目的探讨胸腔镜手术治疗早期非小细胞肺癌的临床疗效。方法选取2013—2014年中国人民解放军第323医院收治的早期NSCLC患者60例,根据患者意愿分为对照组(n=28)和观察组(n=32)。对照组患者采用传统开胸手术治疗,对照组采用胸腔镜下纵膈淋巴结清扫术治疗。比较两组患者各项手术情况、并发症发生情况及癌症治疗功能性量表(FACT-L)得分。结果观察组患者手术时间和住院时间短于对照组,术中出血量和术后引流量低于对照组、并发症发生率低于对照组(P<0.05)。术前两组患者身体状况、情感状况、功能状况、社会或家庭状况、附加状况评分及总分比较,差异无统计学意义(P>0.05)。术后两组患者社会或家庭状况评分比较,差异无统计学意义(P>0.05);观察组患者身体状况、情感状况、功能状况、附加状况评分及总分高于对照组(P<0.05)。结论胸腔镜手术治疗早期非小细胞肺癌的临床疗效确切,可降低患者的并发症发生率,提高患者术后生活质量。
Objective To investigate the clinical efficacy of thoracoscopic surgery for early non-small cell lung cancer. Methods Sixty patients with early stage NSCLC admitted from the 323st Hospital of Chinese People’s Liberation Army from 2013 to 2014 were selected and divided into control group (n = 28) and observation group (n = 32) according to their wishes. Patients in the control group were treated by conventional thoracotomy, while those in the control group were treated by thoracoscopic mediastinal lymph node dissection. The operation conditions, complications and FACT-L scores of the two groups were compared. Results The operation time and hospital stay in observation group were shorter than those in control group. The amount of bleeding and postoperative drainage were lower in the observation group than in the control group. The incidence of complications was lower than that of the control group (P <0.05). There were no significant differences in physical status, emotional status, functional status, social or family status, additional status score and total score between the two groups before operation (P> 0.05). There was no significant difference in scores of social status or family status between the two groups (P> 0.05). The physical status, emotional status, functional status, additional status score and total score of the observation group were higher than those of the control group (P <0.05) . Conclusions Thoracoscopic surgery for early non-small cell lung cancer has definite curative effect, which can reduce the incidence of complications and improve postoperative quality of life.