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目的 寻求膀胱癌术后有效的治疗方法。方法 对行保留膀胱手术治疗的 4 3例膀胱癌患者 ,术后采用羟基喜树碱 (HCPT)行膀胱灌注治疗 ,并与同期其他药物灌注者进行比较。结果 随访 4 0例 ,除 3例灌注不及一个疗程者以外 ,复发 5例 ,复发率为 13.5 % ,优于同期内其他药物灌注的预防效果 ,并发症和副作用极轻。结论 HCPT灌注治疗膀胱癌术后患者有较好的疗效 ,毒副作用少而轻 ,明显优于其他灌注药物
Objective To seek effective treatment of bladder cancer after surgery. Methods Forty-three patients with bladder cancer who had undergone bladder surgery were treated with HCPT for bladder irrigation and compared with other drug-infusion patients during the same period. Results All the patients were followed up for 40 cases. Recurrence was found in 5 cases with recurrence rate of 13.5% except 3 cases with less than one course of treatment, which was better than other drugs in the same period. The complications and side effects were extremely mild. Conclusions HCPT infusion has a good curative effect in patients with bladder cancer after operation, with fewer side effects and lighter toxic effects than other perfusion drugs