作者们应用电子显微镜对4例耳根治术后病人的胆脂瘤基质和周围基质进行了研究,在石蜡切片中基质被分为三层。发现位于基底膜表面的上皮。基底细胞有大和小两种形式,在颗粒层中细胞间的接触主要借助于桥粒来实现。在此层有时见到个别伴有大量核糖体的白细胞和个别的郎罕氏细胞。在角质层中间见有亮的空隙,这可能是由于溶解物质作用的结果。周围基质则是纤维结缔组织和血管,有时伴有网织红细胞。作者们得出如下结论:胆脂瘤基质有着与外耳道扁平上皮相同的结构并有角化趋向,同时还 The authors studied the cholesteatoma matrix and surrounding stroma of 4 patients with post-radical mastectomy using an electron microscope, in which the stroma was divided into three layers. Found in the basement membrane surface epithelium. Basal cells are large and small two forms, in the granular layer of contact between cells mainly by means of desmosomes to achieve. Occasionally, individual white blood cells accompanied with a large number of ribosomes and individual Langerhans cells are sometimes seen at this level. There are bright voids in the middle of the stratum corneum, which may be due to the action of dissolved substances. The surrounding matrix is ​​fibrous connective tissue and blood vessels, sometimes accompanied by reticulocytes. The authors conclude that the cholesteatoma stroma has the same structure as the flattened epithelium of the external auditory meatus and has keratinization tendency