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目的 观察脂调康胶囊对高脂血症患者血清肿瘤坏死因子 α(TNF α)的影响。方法 采用随机、单盲、阳性药平行对照方法将 186例高脂血症患者分成 2组 ,治疗组 12 4例 ,对照组 6 2例。治疗组用脂调康胶囊 ,对照组用脂必妥片。测定 2组治疗前后TNF α的变化。结果 2组治疗后血清TNF α均较治疗前显著降低 (P <0 .0 0 1) ;而治疗后 2组间比较 ,治疗组血清TNF α降低较对照组有显著性差异 (P <0 .0 5 )。结论 脂调康胶囊通过降低TNF α含量 ,减轻其对机体的损伤 ,防止动脉粥样硬化等疾病的形成。
Objective To observe the effect of Zhi Tikang capsule on serum tumor necrosis factor α (TNF α) in patients with hyperlipidemia. Methods A total of 186 patients with hyperlipidemia were divided into two groups by randomized, single-blind and positive drug parallel control method. The treatment group (122 cases) and the control group (62 cases). The treatment group was treated with Zhitongkang capsule and the control group was treated with Zhibutuo tablet. The changes of TNFα in two groups before and after treatment were measured. Results After treatment, the levels of serum TNFα in both groups were significantly lower than those before treatment (P <0.01). After treatment, the serum levels of TNFα in the two groups were significantly lower than those in the control group (P <0.01). 0 5). Conclusion Zhitiaokang Capsule can reduce the damage to the body and prevent the formation of diseases such as atherosclerosis by reducing the content of TNFα.