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目的探讨专项整治管理对医院抗菌药物合理使用中的应用效果。方法:为了提高抗菌药使用的规范性,宁海县中医医院对抗菌药实施综合专项整治活动,措施有责任制管理、加强对药师的管理、加大抗菌药物使用监控等,比较专项整治前后抗菌药物的使用率、使用强度、清洁手术患者预防性使用抗菌药物等情况。结果:专项整治活动后,门诊及住院抗菌药的使用率、使用强度、清洁手术患者预防性使用抗菌药物、抗菌药物费用比例等均低于整治前。门诊及住院的抗菌药物的使用合理情况高于整治前。抗菌药物使用的总频度、非限制使用级、限制使用级和特殊使用级抗菌药物的使用显著低于整治前。结论:抗菌药物的专项整治活动有效提高了抗菌药物使用的规范性和合理性,避免了抗菌药物滥用、错用的情况发生。
Objective To explore the effect of special rectification and management on the rational use of antimicrobial agents in hospitals. Methods: In order to improve the normative use of antimicrobial drugs, Ninghai Hospital of Traditional Chinese Medicine to carry out comprehensive anti-bacterial drugs special rectification activities, measures of responsibility management, to strengthen the pharmacist management, increase the use of antimicrobial drug monitoring, compared to special treatment before and after antimicrobial agents The usage rate, the intensity of use and the prophylactic use of antimicrobials in patients undergoing clean operation. Results: After the special remediation activities, the utilization rate of outpatient and inpatient antibacterials, the intensity of use, the prophylactic use of antibacterials in the patients undergoing clean operation and the proportion of the cost of antibacterial drugs were lower than those before remediation. Outpatient and hospital use of antimicrobial agents is more reasonable than before remediation. The overall frequency of use of antimicrobial agents, non-restricted use level, restricted use level and the use of special-use antibacterials were significantly lower than those before remediation. Conclusion: The special rectification activities of antimicrobial agents effectively improve the standardization and rationality of antimicrobial use, avoiding the abuse of antimicrobial agents and the misuse of antimicrobial agents.