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目的:探讨观察吡格列酮联合二甲双胍治疗新诊断的2型糖尿病的临床效果。方法:选择2013年4月至2013年10月期间经我院治疗的89例新诊断的2型糖尿病患者,将全部患者随机分为观察组46例和对照组43例。观察组在饮食及运动治疗基础上加用吡格列酮片与二甲双胍片;对照组在饮食及运动治疗基础上仅服用二甲双胍片,比较两组临床疗效。结果:观察组治疗后的总有效率达97.83%,明显高于对照组治疗后的总有效率88.37%(P<0.05);两组患者治疗过程中均无严重不良反应发生。结论:吡格列酮联合二甲双胍在临床治疗中能有效改善新诊断的2型糖尿病患者的血糖水平,具有很好的治疗效果,值得推广。
Objective: To investigate the clinical effect of pioglitazone combined with metformin on newly diagnosed type 2 diabetes mellitus. Methods: A total of 89 newly diagnosed type 2 diabetic patients treated in our hospital from April 2013 to October 2013 were randomly divided into observation group (46 cases) and control group (43 cases). The observation group added pioglitazone tablets and metformin tablets on the basis of diet and exercise therapy. The control group only took metformin tablets on the basis of diet and exercise therapy, and compared the clinical curative effect of the two groups. Results: The total effective rate of the observation group after treatment was 97.83%, which was significantly higher than that of the control group after treatment (88.37%, P <0.05). No serious adverse reactions occurred in the two groups during treatment. Conclusion: Pioglitazone combined with metformin can effectively improve the blood glucose level in newly diagnosed type 2 diabetic patients and has good curative effect. It is worth to be popularized.