目的　探讨超重及肥胖症患者合并脂肪肝的发病情况及其危险因素 ,减重治疗对肥胖症患者脂肪肝的逆转作用。方法　 2 2 0例超重及肥胖症患者进行血生化、肝脏B超检查 ,其中 45例肥胖症患者接受为期 1年减重治疗 ,治疗前后测定体重 ,进行 75g葡萄糖耐量试验 ,同时测定血真胰岛素水平 ,血生化及肝脏B超检查 ,评价减重治疗后脂肪肝转归的影响因素。结果　 75 9%的超重及肥胖症患者患有不同程度的脂肪肝 ,患者的体重指数、年龄、服糖后 2h血糖水平、服糖后 1h真胰岛素水平、腰围、低密度脂蛋白胆固醇水平是脂肪肝的危险因素。经过减重治疗 ,65 7%肥胖症患者的脂肪肝得到了改善 ,患者的血清转氨酶水平也有显著下降。结论　脂肪肝是肥胖症患者常见的并发症之一 ,减轻体重是治疗肥胖症患者脂肪肝有效的治疗手段 Objective To investigate the incidence and risk factors of fatty liver in overweight and obesity patients and the reversal effect of weight loss treatment on fatty liver in obesity patients. Methods Twenty-two patients with overweight and obesity underwent blood biochemistry and liver ultrasonography. Forty-five obese patients underwent one-year weight loss treatment. Body weight was measured before and after treatment. Glucose tolerance test was performed on 75 g glucose and blood insulin level , Blood biochemistry and liver B-ultrasound, evaluation of factors affecting the outcome of fatty liver after weight loss treatment. Results 75.9% of overweight and obese patients had different degrees of fatty liver. The body mass index, age, blood glucose level at 2h after oral administration, true insulin level at 1h after oral administration, waist circumference and LDL-C level Liver risk factors. After weight loss treatment, 65.7% of patients with fatty liver fatty liver has been improved, the patient’s serum aminotransferase levels also dropped significantly. Conclusions Fatty liver is one of the most common complication of obesity. Weight loss is an effective treatment for fatty liver in obese patients