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作者采用血小板自动平衡聚集仪,建立血浆血小板活化因子(PAF)的生物活性测定法,检测了27例失代偿期肝硬化患者血浆PAF含量;同时测定血浆内毒素含量,以探讨肝硬化时PAF改变与内毒素血症的关系及临床意义。结果表明,肝硬化组PAF含量(5.34±1.94ng/ml)显著高于正常对照组 (1.18±0.24
The author used platelet auto-balance aggregator to establish bioassay of plasma platelet-activating factor (PAF) and detected plasma PAF levels in 27 patients with decompensated cirrhosis. Plasma endotoxin levels were also measured to investigate the effect of PAF Change and the relationship between endotoxemia and clinical significance. The results showed that PAF content in liver cirrhosis group (5.34 ± 1.94ng / ml) was significantly higher than that in normal control group (1.18 ± 0.24