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目的:探讨垂体后叶素在腹腔镜下输卵管妊娠挤压取胚术中的临床效果。方法:将2010年1月～2011年12月在钦州市妇幼保健院确诊为未破裂型输卵管妊娠(除输卵管间质部妊娠外)、有生育要求、具备保留输卵管条件的150例患者分为观察组和对照组1、2。观察组(50例)先行输卵管挤压妊娠物清除术,再将垂体后叶素6 U注射于妊娠部位输卵管浆肌层;对照组1(50例)只行输卵管挤压妊娠物清除术;对照组2(50例)在输卵管妊娠部位注射垂体后叶素后再行切开取胚术。比较3组输卵管保留成功率、手术出血量、手术时间、术后最高体温、持续性异位妊娠发生率等。结果:观察组手术时间、术中出血量明显少于对照组1(P<0.01),与对照组2比较差异无统计学意义(P>0.05);观察组术后输卵管保留成功率明显高于对照组1(P<0.01),患侧输卵管通畅率明显高于对照组1、2(P<0.01);3组术后最高体温及持续性异位妊娠发生率比较差异无统计学意义(P>0.05)。结论:腹腔镜下输卵管挤压妊娠物清除术后再将垂体后叶素6 U注射于妊娠部位输卵管浆肌层能有效减少术中出血量,缩短手术时间,提高输卵管保留成功率及术后输卵管通畅率,手术安全、可靠,副作用少,值得推广。
Objective: To investigate the clinical effect of vasopressin in laparoscopic tubal pregnancy. Methods: From January 2010 to December 2011 in Qinzhou Maternal and Child Health Hospital was diagnosed as unruptured tubal pregnancy (except tubal interstitial pregnancy), have fertility requirements, with retention of tubal conditions of 150 patients were divided into observation Groups and control groups 1,2. In the observation group (50 cases), tubal excretion was performed before pregnancy, and 6 U of vasopressin was injected into the tubal myometrium at the pregnancy site. Control group 1 (50 cases) Group 2 (50 cases) in the tubal pregnancy after injection of pituitrin and then cut open embryo surgery. The success rate of tubal retention, operative bleeding, operation time, postoperative maximal body temperature and the incidence of persistent ectopic pregnancy were compared. Results: The operation time and intraoperative blood loss in observation group were significantly less than those in control group 1 (P <0.01), but there was no significant difference between control group 2 and observation group (P> 0.05). The success rate of tubal retention in observation group was significantly higher than that of control group 1 In control group 1 (P <0.01), the tubal patency rate was significantly higher than that in control group 1 and 2 (P <0.01). There was no significant difference in postoperative maximal body temperature and persistent ectopic pregnancy among the three groups (P > 0.05). Conclusion: Laparoscopic tubal squeeze of pregnancy after the removal of pituitary vasopressin 6 U in the tubal muscle layer of pregnancy can effectively reduce the amount of intraoperative bleeding, shorten the operation time and improve the success rate of tubal retention and tubal postoperative Patency, surgical safety, reliability, fewer side effects, it is worth promoting.