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目的探讨早产胎膜早破与新生儿宫内感染性肺炎的相关性。方法采用回顾性分析方法,收集2012年1月-2014年12月在该院产科住院分娩的胎膜早破早产儿且全部转入新生儿科治疗的326例为研究对象,根据宫内感染性肺炎诊断标准分为肺炎组88例和非肺炎组238例。分析胎膜早破与宫内感染性肺炎及相关并发症的相关性。结果肺炎组母血白细胞计数(WBC)、C-反应蛋白(CRP)升高及心动过速、绒毛膜羊膜炎发生率明显高于非肺炎组,且早产胎膜早破发生时孕周越小,潜伏期越长,新生儿越易发生宫内感染性肺炎,同时肺炎组新生儿发生宫内感染败血症、呼吸窘迫综合征(RDS)、新生儿窒息、早产儿脑病等相关并发症的比例也明显高于非肺炎组,差异均有统计学意义(均P<0.05)。结论胎膜早破早产儿与宫内感染性肺炎存在一定的相关性,应引起注意,积极防治。
Objective To investigate the relationship between preterm premature rupture of membranes and neonatal intrauterine infection pneumonia. Methods A retrospective analysis method was used to collect 326 cases of premature rupture of membranes in obstetrics and gynecology hospitalized from January 2012 to December 2014 and all of them were transferred to neonatal department for treatment. According to intrauterine infection pneumonia The diagnostic criteria were divided into pneumonia group 88 cases and non-pneumonia group 238 cases. Analysis of the correlation between premature rupture of membranes and intrauterine infection pneumonia and related complications. Results The maternal blood leucocyte count (WBC), C-reactive protein (CRP), tachycardia and chorioamnionitis in pneumonia group were significantly higher than those in non-pneumonia group and the gestational age at preterm premature rupture of membranes , The longer the incubation period, the more likely neonates to develop intrauterine infection pneumonia, pneumonia group neonatal intrauterine infection sepsis, respiratory distress syndrome (RDS), neonatal asphyxia, premature encephalopathy and other related complications also significantly Higher than non-pneumonia group, the difference was statistically significant (P <0.05). Conclusion Premature rupture of membranes premature children and intrauterine infection pneumonia there is a certain correlation should be drawn attention to active prevention and treatment.