早孕期经腹绒毛取材在产前诊断中的应用

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早孕期的介入性产前诊断方法主要是绒毛取材(chorionic villus sampling,CVS),CVS 的方式主要有经宫颈CVS(transcervical CVS,TC-CVS)和经腹 CVS(transabdominalCVS,TA-CVS)两种。长期以来,国内早孕期 CVS 均采用 TC-CVS,该法取材量少、母体组织污染率高、手术并发症发生率高,因而难以在临床推广应用。我院从1994年起,开展在 B超引导下的早孕期 TA-CVS,该法操作简便,取材量充足,母体组织污染率低,手术并发症发生率低,便于在临床上广泛开展,现将结果报道如下。一、资料与方法1.资料来源:选择2000年1月至2004年4月在我院产前咨询门诊就诊的、具有明确产前诊断指征的早孕期妇女219例,年龄21~43岁,平均32岁,孕9~14周,平均11周, Interventional prenatal diagnosis of early pregnancy is mainly chorionic villus sampling (CVS), CVS mainly by the cervical CVS (transcervical CVS, TC-CVS) and transabdominal CVS (TA-CVS) two . For a long time, TCS CVS were used in early pregnancy in China. This method has the advantages of less drawing material, high rate of maternal tissue contamination and high incidence of surgical complications, which makes it difficult to promote clinical application. Our hospital from 1994, carried out in the B-guided early pregnancy TA-CVS, the method is simple and convenient, adequate amount of material, low maternal tissue contamination, the incidence of complications is low, easy to widely carried out in the clinic, and now The results are reported below. I. Materials and Methods 1. Source: Select 219 cases of early pregnant women with definite prenatal diagnosis indications from January 2000 to April 2004 in prenatal consultation clinic in our hospital, aged 21-43 years old, An average of 32 years old, 9 to 14 weeks of pregnancy, an average of 11 weeks,
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