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丝裂霉素C（MMC）是治疗多种肿瘤的有效药物。将MMC与肿瘤单抗连接，有可能提高MMC的治疗效果。为使每个单抗分子携带多个MMC而不影响抗体活性，本研究应用肝癌单抗HePamal作为药物载体，将MMC联于人血清白蛋白（HSA），然后将HSA与抗体联接，并对日本学者介绍的MMC活化条...
Mitomycin C (MMC) is an effective drug for the treatment of many tumors. The MMC and tumor monoclonal antibody connection, may improve the therapeutic effect of MMC. In order to make each mAb carry multiple MMCs without affecting the activity of the antibody, HepAm was used as the drug carrier in this study. The MMC was linked to human serum albumin (HSA), and then the HSA was linked to the antibody. Scholars introduced MMC activation bar ...