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复杂的乙肝病毒外壳含有三种不同基因编码的蛋白质。第一种称为S,为乙肝表面抗原(HBs-Ag),其余两种位于S 基因之前称为前-S(1)和前-S(2)。当前经过深入研究发现这些标志与乙肝病程之间有关,作者通过对急性乙肝和其它慢性肝病检测前-S(1)抗原和前-S(2)抗体,与其它标志相比较,对其诊断和预后进行了讨论。研究了69例患者,急性乙肝14例,HBsAg 阳性的慢性肝炎30例,无症状HBV 携带者25例,急性乙肝患者每20天检测1次,每次分析包括HBsAg、HBsAb、HBcIgMAb、HBeAg、HBeAb、DNA-HBV,前-S(1)抗原和前-S(2)抗体。
The complex hepatitis B virus shell contains proteins encoded by three different genes. The first, called S, is hepatitis B surface antigen (HBs-Ag) and the remaining two are called pre-S (1) and pre-S (2) before the S gene. Currently, after intensive study, we found that these markers are related to the course of hepatitis B. The authors compared the presence of pre-S (1) antigens and pre-S (2) antibodies with other markers in the diagnosis of acute hepatitis B and other chronic liver diseases Prognosis was discussed. We studied 69 patients with acute hepatitis B in 14 cases, 30 HBsAg-positive chronic hepatitis, 25 asymptomatic HBV carriers and 1 in 20 patients with acute hepatitis B. Each analysis included HBsAg, HBsAb, HBcIgMAb, HBeAg, HBeAb , DNA-HBV, pre-S (1) antigen and pre-S (2) antibody.