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本实验用高效液相色谱—电化学检测法及受体配体结合法观察五味子醇甲对大鼠脑内单胺类递质及其受体的影响,结果表明五味子醇甲可使大鼠纹状体及下丘脑多巴胺含量明显增加,提示五味子醇甲的中枢抑制作用可能与多巴胺系统有一定联系。
The experiment using high performance liquid chromatography - electrochemical detection method and receptor ligand binding observed schizandrin alcohol monoamine neurotransmitter and its receptors in rats brain, the results show that schizandrin can rat pattern Body and hypothalamus dopamine increased significantly, suggesting that schisandrin A central inhibitory effect may be related to the dopamine system.