小剂量~(131)I多次给药治疗甲状腺功能亢进症临床研究

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目的对于小剂量~(131)I多次给药治疗甲状腺功能亢进症临床效果进行研究。方法选取我院甲状腺亢进症患者82例为研究对象,将其随机分为对照组和实验组各41例。对照组患者一次性服用小剂量~(131)I进行治疗;实验组患者分多次服用小剂量~(131)I进行治疗。对比观察两组患者治疗前后甲功五项的检查结果,以及治疗后的临床疗效。结果实验组患者经多次服用小剂量~(131)I进行治疗后,患者的甲状腺功能恢复较快,治疗周期短,患者临床治愈率较对照组相比更高。两组患者的差异具有统计学意义(P<0.05)。结论实验组患者多次服用小剂量~(131)I进行治疗,患者的治疗效果更好。持续给药一个疗程,检查两组患者的甲功五项指标,实验组患者的甲状腺功能恢复更快。因此对于甲亢患者多次服用小剂量~(131)I进行治疗效果明显优于一次性给药的治疗方式。 Objective To study the clinical effect of multiple doses of ~ (131) I in the treatment of hyperthyroidism. Methods 82 cases of hyperthyroidism in our hospital were selected as the research object, which were randomly divided into control group and experimental group of 41 cases. Patients in the control group were treated with low dose of ~ (131) I once; patients in the experimental group were treated with 131 I for several times. Comparison of two groups of patients before and after treatment of thyroid function five test results, and the clinical efficacy after treatment. Results The patients in the experimental group were treated with 131I I for several times, and their thyroid function recovered quickly and the treatment period was short. The clinical cure rate was higher in the experimental group than in the control group. The differences between the two groups were statistically significant (P <0.05). Conclusions Patients in the experimental group were treated with low dose 131I for many times and the treatment effect was better. Continuous administration of a course of treatment, check the two groups of patients with five indicators of thyroid function, the experimental group of patients with thyroid function recovery faster. So for patients with multiple hyperthyroidism taking small doses of 131I treatment was significantly better than the one-time treatment of the treatment.
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