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包涵体肌炎在国内较少报道,本文报告1例散发型包涵体肌炎青年男性患者,病程2年,以四肢远端进行性肌无力、肌萎缩为首发症状。生化检查示肌酸激酶(CK)及其同工酶升高。肌电图示肌原性损伤。肌肉活检发现有边缘着色性空泡,电镜下见肌细胞核中有细丝状包涵物而确诊为包涵体肌炎。本文结合文献,对本病诊断问题加以讨论。
Inclusion body myositis less reported in the country, this article reports a case of sporadic inclusion body myositis young male patients, duration of 2 years to distal limb muscle weakness, muscle atrophy as the first symptom. Biochemical tests showed elevated creatine kinase (CK) and its isoenzymes. Myoelectricity shows myogenic damage. Muscle biopsy found edge-colored vacuoles, electron microscopy, there are filamentous inclusions in the muscle cell nucleus and confirmed as inclusion body myositis. This article combined with the literature on the diagnosis of the disease to be discussed.