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日本东大农学部的桥本周久教授和助手渡部终五等,已研究成功河豚毒素单克隆抗体。因抗体和抗原的结合尚不十分牢固,还不能使河豚毒完全无毒化。但今后可设法改变其结构.制成抗体,供河豚中毒者救命之用。河豚毒素分子量较小,为319。为了能够象认识抗原那样认出抗体,需要将其分子量变成数千以上。因此,渡部等用河豚毒素的诱导体,使毒性很低的河豚毒
Professor Kazuhiro Hashimoto of Japan’s Nagoya Faculty of Agriculture and his assistant Watanabe finished the fifth and so on and have successfully studied tetrodotoxin monoclonal antibodies. Due to the combination of antibodies and antigens is not yet very solid, can not make tetrodotoxin completely non-toxic. However, in the future, we can try to change its structure and make antibodies for the help of puffer poisoning. Tetrodotoxin molecular weight smaller, 319. In order to recognize an antibody like an antigen, its molecular weight needs to be several thousand or more. Therefore, Watanabe and other tetrodotoxin inducers, so that very low toxicity tetrodotoxin