虽然肠道对胆固醇吸收的变异已被证实,但其在糖尿病患者胆固醇代谢中的作用仍不明了。我们过去曾报道了糖尿病患者餐后载脂蛋白B48(apoB48)的一种改变模式,目前已建立一种载脂蛋白B-48的定量测定方法。本研究对apoB48进行了测定,在糖尿病患者胆固醇的肠道转运中,apoB48是必需的载脂蛋白。我们对8例非胰岛素依赖型糖尿病患者(NIDDM)平均HbAlc7.4±0.6％)及10例非糖尿病患者,在其空腹以及进食1300千卡后的2、4、6和8小时分别采取血液标本进行测定。 Although the variation of intestinal absorption of cholesterol has been confirmed, its role in the cholesterol metabolism of diabetic patients remains unclear. We have reported in the past a pattern of altered postprandial apolipoprotein B48 (apoB48) in diabetic patients and a quantitative assay for apolipoprotein B-48 has been established. The present study determined apoB48, an apoB48 essential for apolipoprotein cholesterol transport in diabetic gut. We averaged 8.4 ± 0.6% of HbA1c in 8 non-insulin dependent diabetic patients (NIDDM) and 10 nondiabetic patients). Blood samples were taken at 2, 4, 6 and 8 hours after fasting and 1,300 kcal respectively Measurement was performed.