论文部分内容阅读
目的:分析和探究甲氨蝶呤联合米非司酮对于治疗异位妊娠患者的临床方法和效果。方法:随机选择了2015年4月-2016年4月我院收治的120例异位妊娠患者作为研究对象,将其分为对照组和实验组,对照组患者仅给予甲氨蝶呤治疗,而实验组患者在对照组的基础上又给予了米非司酮治疗,然后对两组患者的临床症状和治疗效果进行记录和对比。结果:实验组患者治疗总有效率达到了98.33%,明显高于对照组的90.0%,治疗后,实验组患者的血β-HCG值(1203.8±19.4)IU/L和妊娠包块直径(1.3±0.5)cm均明显降低,并低于对照组的(1359.4±20.3)IU/L、(2.1±0.9)cm,同时实验组患者不良反应发生率(5.0%)低于对照组的(18.33%)他们之间的数据差异具有统计学意义(P<0.05)。结论:在对异位妊娠患者进行临床治疗时,为其提供甲氨蝶呤联合米非司酮治疗,不仅可以有效改善患者的临床症状,而且还能提高患者的治疗效果,降低不良反应的发生。
Objective: To analyze and explore the clinical efficacy and effects of methotrexate combined with mifepristone in the treatment of patients with ectopic pregnancy. Methods: A total of 120 ectopic pregnancy patients admitted to our hospital from April 2015 to April 2016 were randomly selected as the control group and experimental group. Patients in the control group were treated with methotrexate only. Patients in the experimental group were treated with mifepristone on the basis of the control group, and then the clinical symptoms and treatment effects of the two groups were recorded and compared. Results: The total effective rate of the experimental group was 98.33%, which was significantly higher than that of the control group (90.0%). After treatment, the β-HCG value of the experimental group was (1203.8 ± 19.4) IU / L and the diameter ± 0.5 cm in the control group were significantly lower than those in the control group (1359.4 ± 20.3 IU / L, 2.1 ± 0.9 cm). The incidence of adverse reactions in the experimental group (5.0%) was lower than that in the control group (18.33% ) There was statistical difference between them (P <0.05). Conclusion: Methotrexate combined with mifepristone can not only effectively improve the clinical symptoms of patients during ectopic pregnancy, but also improve the therapeutic effect and reduce the incidence of adverse reactions .