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目的 :研究良性前列腺增生患者行经尿道前列腺电汽化术 ( TUEVP)对前列腺特异性抗原 ( PSA)值的影响。方法 :经直肠超声测量 3 0例前列腺增生患者的前列腺体积 ,均行 TUEVP。分别于术前及术后第 1、3、5天及 1个月检测患者血清中 PSA值。并用中位数±四分位间距成组设计的秩和检验进行显著性检验。结果 :术后第 1天血清 PSA值较术前明显升高 ( P<0 .0 0 1) ,其后逐渐下降 ,至术后 1个月血清 PSA值降至基线水平 ,与术前比较无显著性差异 ( P>0 .0 5 )。结论 :TUEVP会使血清 PSA值升高 ,以术后第 1天影响最明显 ,维持约 1个月 ,其后逐渐下降至一个稳定、较低的水平。所以 ,临床上如要获得一个正确而有意义的 PSA值 ,至少要等到 TU EVP术后 1个月。
Objective: To study the effect of transurethral electrovaporization of the prostate (TUEVP) on prostate-specific antigen (PSA) in patients with benign prostatic hyperplasia. Methods: Prostate volume in 30 benign prostatic hyperplasia patients was measured by transrectal ultrasound, and TUEVP was performed. Serum PSA levels were measured preoperatively and on days 1, 3, 5, and 1 postoperatively. Significant tests were performed using the rank sum test of the median ± quartile spacing in a group design. Results: On the first postoperative day, the serum PSA level was significantly higher than that before the operation (P <0.01), and then decreased gradually. The serum PSA decreased to the baseline level one month after the operation, Significant difference (P> 0.05). CONCLUSION: TUEVP will increase the serum PSA level, with the most obvious effect on the first postoperative day, maintaining for about 1 month and then gradually decreasing to a stable and low level. Therefore, clinically to obtain a correct and meaningful PSA value, at least until TU EVP 1 month after surgery.