恶性高热为全麻中罕见但致命的合并症,其特征为体温迅速进行性上升,常伴有全身肌肉强直。在许多有关报告中,引起恶性高热的麻醉药品中,以氟烷及司可林最常见,亦有应用甲氧氟烷,圜丙烷及三氯乙烯后发生的。此外也可因一些非麻醉性药物(如治疗精神性疾患的某些药物)所引起。一、简史Turttle 等1900年曾报告术后因暴热而死亡的病例,1960及1962年相继有人报告一澳大利亚家族在 Malignant hyperthermia is a rare but fatal comorbid complication of general anesthesia characterized by rapid and progressive increase in body temperature, often accompanied by generalized muscular rigidity. Of the many reports concerned, among the narcotic drugs that cause the fever of high fever, the most common ones are halothane and sclerodine, and the ones that occur after the use of methoxyflurane, propane and trichlorethylene. In addition, it can also be caused by some non-narcotic drugs, such as certain drugs for the treatment of mental disorders. First, a brief history Turttle et al1900 reported cases of postoperative fever due to death, 1960 and 1962 have been reported in an Australian family