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目的:调查急性冠状动脉综合征(ACS)患者焦虑情绪的患病率,了解其对患者生活质量的影响。方法:入选ACS患者454例,运用医院焦虑抑郁量表焦虑亚量表(HADS-A)评分分为焦虑组(HADa≥6分)和非焦虑组(HADa<6分),并使用SF-36对其生活质量进行评估。结果:454例中247例为焦虑组;207例为非焦虑组。患病率为54.4%;2组人群血脂及炎症因子水平差异无统计学意义(P>0.05);焦虑组全部生活质量评分均显著低于非焦虑组(P<0.01);HADS-A焦虑评分与患者生活质量评分呈显著负相关(P<0.01),进一步Logistic回归分析未见炎症因子与ACS患者焦虑的发生有明显相关性。结论:ACS患者焦虑情绪较为常见,使其生活质量明显降低。
Objective: To investigate the prevalence of anxiety in patients with acute coronary syndrome (ACS) and to understand its impact on the quality of life of patients. Methods: Forty-five ACS patients were enrolled in this study. HADS-A scores were divided into anxiety group (HADa≥6) and non-anxiety group (HADa≤6) using SF-36 Evaluate their quality of life. Results: Among the 454 cases, 247 were anxiety groups and 207 were non-anxiety groups. The prevalence rate was 54.4%. There were no significant differences in the level of blood lipid and inflammatory cytokines among the two groups (P> 0.05). The quality of life quality of anxiety group was significantly lower than that of non-anxiety group (P <0.01) Negatively correlated with the quality of life of patients (P <0.01). Logistic regression analysis showed no significant correlation between inflammatory factors and the occurrence of anxiety in patients with ACS. Conclusion: Anxiety is more common in patients with ACS, which significantly reduces the quality of life.