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报告11例慢性正己烷中毒患者,临床主要表现为四肢末端疼痛、麻木、无力、泌汗异常、痛温觉减退、腱反射减弱和肌肉萎缩等,神经电生理检查9例有周围神经的损害,即运动神经和感觉神经传导速度减慢、动作电位的波幅异常及交感神经皮肤电反应异常。参照诊断标准(GBZ84—2002), 2例诊断为重度中毒,4例中度中毒,5例轻度中毒。入院后给予B族维生素、神经生长因子(金路捷)、地塞米松、血栓通等药物治疗,于3个月后症状开始缓解。
Report of 11 patients with chronic n-hexane poisoning, the clinical manifestations of extremities distal pain, numbness, weakness, abnormal sweat, pain and temperature decline, decreased tendon reflex and muscle atrophy, nerve electrophysiological examination in 9 cases of peripheral nerve damage, That motor and sensory nerve conduction velocity slowed down, the abnormal amplitude of action potential and sympathetic electrical skin reaction abnormalities. Reference to diagnostic criteria (GBZ84-2002), 2 cases were diagnosed as severe poisoning, 4 cases of moderate poisoning, 5 cases of mild poisoning. B vitamins, nerve growth factor (Jin Lu Jie), dexamethasone and thrombus were given after treatment. The symptoms began to relieve after 3 months.