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目的 :探讨喹诺酮类药物的不良反应情况,并对临床用药进行指导。方法 :选取某医院2014.5-2016.5所收治的喹诺酮类药物不良反应患者共100例作为研究对象,对患者的临床资料进行回顾性分析,分析喹诺酮类药物不良反应并提出临床用药注意事项。结果 :喹诺酮类药物的不良反应大多以皮肤、神经和消化系统反应为主要发生方式,并且静脉给药方式与口服用药方式相比,其用药不良反应明显较大。结论 :在明确喹诺酮类药物不良反应情况的基础上,医护人员对患者及家属开展详细的用药指导,能够最大程度上减少不良反应的发生几率,提高临床用药的合理性,推进临床医学的发展。
Objective: To investigate the adverse reactions of quinolones and to guide the clinical medication. Methods: A total of 100 cases of quinolone adverse reactions admitted to a hospital from May 2014 to May 2016 were selected as the research object. The clinical data of the patients were retrospectively analyzed. The adverse reactions of quinolones were analyzed and the precautions for clinical use were proposed. Results: Most of the adverse reactions of quinolones occurred mainly in the skin, nerve and digestive system reactions, and the adverse drug reactions were significantly greater in intravenous administration compared with oral administration. Conclusion: On the basis of knowing the adverse reactions of quinolones, the medical staff can provide detailed guidance to patients and their families to minimize the incidence of adverse reactions, improve the rationality of clinical medication and promote the development of clinical medicine.