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目的:分析CKD患者冠状动脉钙化与临床指标的相关性,探讨其发生的危险因素。方法:选取473例曾在我院行冠脉CT检查的CKD及非CKD患者,通过收集其生化指标及冠脉CT检查结果,分析CKD患者冠状动脉钙化与临床检查指标的关系。结果:患者冠状动脉钙化积分(CACs)与年龄、尿素氮、肌酐水平、血磷水平和钙磷乘积呈正相关(P<0.05),与肾小球滤过率和血红蛋白呈负相关(P<0.05)。结论:年龄、尿素氮和血磷是患者冠脉发生钙化的独立危险因素,年龄、肌酐水平、肾小球滤过率和血磷水平与冠状动脉钙化严重程度有线性关系。
Objective: To analyze the correlation between coronary artery calcification and clinical parameters in patients with CKD and to explore the risk factors. Methods: 473 CKD and non-CKD patients who had coronary CT scan in our hospital were selected. The biochemical indexes and coronary CT examination results were collected to analyze the relationship between coronary artery calcification and clinical examination indexes in CKD patients. Results: Coronary artery calcification scores (CACs) were positively correlated with age, urea nitrogen, creatinine level, serum phosphorus level and calcium and phosphorus products (P <0.05), but negatively correlated with glomerular filtration rate and hemoglobin ). CONCLUSION: Age, urea nitrogen and phosphorus are the independent risk factors of coronary artery calcification. Age, creatinine level, glomerular filtration rate and phosphorus level have a linear relationship with the severity of coronary artery calcification.