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越来越多的研究表明,肠屏障受损与2型糖尿病以及非特异性免疫系统激活有关。肠屏障受损可引起机体非特异性炎性激活并促进2型糖尿病的进展,2型糖尿病又可反作用于肠道而引起肠屏障受损。该文对其中的作用过程及其机制进行论述,对肠屏障受损与2型糖尿病关系的研究进展作简要的综述,并提出相应的改善措施,以期为糖尿病防治工作提供新的方向。
A growing body of research shows that impaired gut barrier is associated with type 2 diabetes and activation of a nonspecific immune system. Impaired intestinal barrier can cause non-specific inflammatory activation of the body and promote the progress of type 2 diabetes, type 2 diabetes can cause intestinal barrier and cause damage to the intestinal barrier. The article discusses the course of action and its mechanism, and briefly reviews the research progress of the relationship between intestinal barrier damage and type 2 diabetes and puts forward corresponding improvement measures in order to provide a new direction for the prevention and treatment of diabetes.