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目的探讨立止血在治疗上消化道出血中的止血作用及临床应用。方法回顾性分析我院自2008年1月至2009年12月共收治上消化道86例患者,随机分为治疗组43例,对照组43例,分别采用立止血和奥美拉唑(洛赛克)+氨甲苯酸(止血芳酸)治疗,进行临床观察。结果进行疗效判定,治疗组显效24例,占55.9%,有效17例,占39.5%,无效2例,占4.6%,总有效率为95.4%;对照组显效22例,占51.1%,有效16例,占37.2%,无效5例,占11.7%,总有效率为88.3%;就出血率比较,治疗后24h继续出血率无显著差异性,治疗后24～48h与72h继续出血人数及出血率治疗组明显低于对照组(P<0.05),两组之间有明显的差异显著性。有13例患者出现不同程度的腹痛、排便次数增多,恶心、头晕等症状,减少或停止药物用量后,症状消失;没有出现任何心、肝、肾等不良反应和并发症。结论立止血具有止血快,维持时间长,而且使用方便、安全,不良反应少,值得在临床中推广使用。
Objective To investigate the hemostatic effect of clopidogrel in the treatment of upper gastrointestinal bleeding and its clinical application. Methods Retrospective analysis of our hospital since January 2008 to December 2009 were admitted to the upper gastrointestinal tract of 86 patients were randomly divided into treatment group 43 cases, control group 43 cases, respectively, the use of Ostomy and omeprazole (Loser G) + ammonia toluic acid (hemostatic aromatherapy) treatment, clinical observation. Results The curative effect was evaluated in 24 cases (55.9%), effective in 17 cases (39.5%), ineffective in 2 cases (4.6%) and total effective rate (95.4%) in control group Cases, accounting for 37.2%, 5 cases were ineffective, accounting for 11.7%, the total effective rate was 88.3%; bleeding rate comparison, 24h after treatment continued bleeding rate was no significant difference between 24 ~ 48h and 72h after treatment continued bleeding number and bleeding rate The treatment group was significantly lower than the control group (P <0.05), there was significant difference between the two groups. There are 13 patients with varying degrees of abdominal pain, increased frequency of bowel movements, nausea, dizziness and other symptoms, to reduce or stop the amount of medication, the symptoms disappear; no heart, liver, kidney and other adverse reactions and complications. Conclusion Standing hemostasis with fast bleeding, maintaining a long time, and easy to use, safe, less adverse reactions, it is worth to promote the use of the clinic.