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~(131)I-6β-iodomethyl-19-norcholest-5(10)-en-3β-o1(简称NCL-6-~(131)I)是目前国内外临床应用中认为是较好的肾上腺显影剂,它在肾上腺皮质中的亲和性远较胆固醇为高,为了进一步提高和改进亲肾上腺的功能,曾研究和合成了多种胆固醇的放射性衍生物和研究了不同放射性核素对肾上腺亲和性的影响,以寻求显影剂的结构性质和肾上腺吸取功能间的相互关系。
(131) I-6β-iodomethyl-19-norcholest-5 (10) -en-3β-o1 (NCL-6- 131I) is currently considered to be a good adrenal gland in clinical application at home and abroad Agent, its affinity in the adrenal cortex is much higher than cholesterol, in order to further improve and improve the function of the adrenal glands, has studied and synthesized a variety of radioactive derivatives of cholesterol and studied the effect of different radionuclides on adrenal and The effect of sexuality is sought in the interplay between the structural properties of the developer and adrenal uptake.