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巨噬细胞集落刺激因子是近年来国外学者密切关注的具有抗白念珠菌感染作用的细胞因子 ,它能促进骨髓造血祖细胞分化发育成单核巨噬细胞 ,并增强巨噬细胞粘附吞噬白念珠菌的能力。实验室及临床Ⅰ /Ⅱ期研究表明 ,巨噬细胞集落刺激因子在临床抗白念珠菌感染方面具有良好的应用前景。
Macrophage colony-stimulating factor is a cytokine closely related to Candida albicans infection, which is closely concerned by foreign scholars in recent years. It can promote the differentiation of bone marrow hematopoietic progenitor cells into mononuclear macrophages and enhance macrophage adhesion phagocytosis Candida ability. Laboratory and clinical phase Ⅰ / Ⅱ studies have shown that macrophage colony stimulating factor in clinical anti-Candida infection has a good prospect.