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本文对原发性肝癌和旰硬变患者血清过氧化氢酶进行测定,并以50例健康志愿者作为对照组,初步探讨其临床意义。 观察组均为本科住院患者。原发性肝癌组44例,男性40例,女性4例,年龄19～65岁,平均43岁;上述患者均符合1977年全国肝癌防治协作会议拟定的诊断标准。肝硬变组32例,男性28例,女性4例,年龄18～65岁,平均44岁;根据病史、体格检查、化验及影象学方面等检查确诊。在观察过程中有合并感染及其它严重并发症者均匀予以除外。对照组为健康志愿者50例,男性27例,女性23例,年龄18～23岁,平均22岁。晨起采空腹静脉血分离血浆,用苏联学者提出的分尤光度法测定血清过氧化氢酶活性。原发性肝癌组为87.1±35.0μmol/100ml,肝硬变组患者为61.0±25.3μmol/100m1,均非常显著高于对照组的39.9±12.2μmol/100m1(P<0.01);原发性肝癌组又非常显著地高于肝硬变组(P<0.01)。
In this paper, serum catalase in patients with primary liver cancer and hernia was determined, and 50 healthy volunteers were used as a control group to explore its clinical significance. The observation group were undergraduate inpatients. The primary liver cancer group consisted of 44 patients, 40 males and 4 females, aged 19-65 years, with an average age of 43 years. All of the above patients met the diagnostic criteria drawn up by the 1977 National Liver Cancer Prevention Collaboration Conference. There were 32 cases of cirrhosis group, 28 males and 4 females, aged 18-65 years old, with an average age of 44 years. They were diagnosed according to medical history, physical examination, laboratory tests, and video examinations. In the observation process, patients with coinfection and other serious complications were uniformly excluded. The control group included 50 healthy volunteers, 27 males and 23 females, aged 18 to 23 years with an average age of 22 years. In the morning, blood was collected from fasting venous blood, and the activity of catalase in serum was determined using a Pythyle-Spectrophotometric method proposed by Soviet scholars. The primary liver cancer group was 87.1±35.0μmol/100ml, and the cirrhosis group was 61.0±25.3μmol/100m1, which was significantly higher than the control group 39.9±12.2μmol/100m1 (P<0.01); primary liver cancer The group was also significantly higher than the cirrhosis group (P<0.01).