论文部分内容阅读
目的:探讨毛细支气管炎患儿发生医院感染的病原学特征及相关危险因素,以期为临床防治提供依据。方法:选择2013年8月到2015年8月我院收治的发生医院感染的毛细支气管炎患儿324例,检验并分析其病原体分布情况,采用多因素Logistic回归方程分析患儿发生医院感染的危险因素。结果:324例患儿中,病毒感染260例,占80.25%,共检出病毒272株,其中呼吸道合胞病毒(RSV)构成比最高,占47.43%,其他依次是柯萨奇病毒(CBV)占9.93%、鼻病毒(RV)占4.04%、腺病毒(ADV)占3.68%及冠状病毒(COV)占3.31%,其他病毒占31.62%;细菌感染64例,占19.75%,共检出细菌73株,其中大肠埃希菌构成比最高,占41.10%,其他依次是金黄色葡萄球菌占31.51%、肺炎克雷伯菌占17.81%、阴沟肠杆菌占6.85%及不动杆菌属占2.74%。多因素分析结果显示,男性、年龄≤6个月、早产儿、父母患有呼吸道疾病及家庭经济状况差是毛细支气管炎患儿发生医院感染的危险因素(P<0.05)。结论:毛细支气管炎患儿发生医院感染的感染源复杂,临床应对不同性别、年龄、是否早产儿、父母是否患有呼吸道疾病及不同家庭经济状况的患儿进行差别治疗。
Objective: To investigate the etiological characteristics and related risk factors of nosocomial infection in children with bronchiolitis, in order to provide the basis for clinical prevention and treatment. Methods: From August 2013 to August 2015, 324 children with bronchiolitis were admitted to our hospital. The distribution of the pathogens was tested and analyzed. The risk of nosocomial infection was analyzed by multivariate logistic regression analysis factor. Results: Among the 324 cases, 260 cases were infected with virus, accounting for 80.25%. A total of 272 strains were detected, of which RSV accounted for the highest proportion (47.43%), followed by Coxsackie virus (CBV) Accounting for 9.93%, rhinovirus (RV) accounting for 4.04%, adenovirus (ADV) accounting for 3.68% and coronavirus (COV) accounting for 3.31%, other viruses accounted for 31.62%; bacterial infection in 64 cases, accounting for 19.75% Among them, Staphylococcus aureus accounted for 31.51%, Klebsiella pneumoniae accounted for 17.81%, Enterobacter cloacae accounted for 6.85% and Acinetobacter accounted for 2.74% . Multivariate analysis showed that males, age ≤6 months, pre-term infants and parents with respiratory diseases and poor family economics were risk factors for nosocomial infection in children with bronchiolitis (P <0.05). Conclusion: The infection of nosocomial infection in children with bronchiolitis is complicated, and the clinical treatment of children with different gender, age, preterm infants, parents with respiratory diseases and different family economic status should be treated differently.