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目的探讨对血尿酸水平急性期缺血性脑卒中患者短期预后的影响。方法选取2011年6月—2015年5月在榆林市第一医院住院治疗的急性期缺血性脑卒中患者1 218例,根据血尿酸水平分为正常组1 008例和异常组210例,比较两组患者短期预后。短期预后影响因素的分析采用Cox回归分析。结果正常组患者短期预后优于对照组(u=-5.781,P<0.001)。糖尿病、高血压、高尿素血症、血尿酸水平异常是急性期缺血性脑卒中患者短期预后不良的独立危险因素,饮酒为独立保护因素(P<0.05)。结论血尿酸水平异常的急性期缺血性脑卒中患者短期预后较差。
Objective To investigate the short-term prognosis of acute ischemic stroke patients with serum uric acid. Methods A total of 1 218 acute ischemic stroke patients hospitalized in Yulin First Hospital from June 2011 to May 2015 were divided into two groups according to the level of serum uric acid: 1 008 cases in normal group and 210 cases in abnormal group Short-term prognosis in both groups. Analysis of short-term prognostic factors using Cox regression analysis. Results The short-term prognosis of patients in the normal group was better than that of the control group (u = -5.781, P <0.001). Diabetes mellitus, hypertension, hyperuricemia and abnormal serum uric acid level were independent risk factors for short-term prognosis in patients with acute ischemic stroke. Alcohol consumption was an independent protective factor (P <0.05). Conclusion Short-term prognosis of patients with acute ischemic stroke with abnormal serum uric acid levels is poor.