1例妊娠22周被诊断为ⅢB期卵巢上皮癌的患者接受初始化疗并维持妊娠:个案报道及文献回顾

来源 :世界核心医学期刊文摘(妇产科学分册) | 被引量 : 0次 | 上传用户:jili1027
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Background.To report a case of succe ssful management of a FIGO stage III endometrioid carcin oma of the ovary di-agnosed during pregnancy at 22weeks of gestation and treated with initial chemotherapy w hile preserving the pregnancy.Case.The patient underw ent a planned ce-sarean section at 34weeks after two c ourses of carboplatin.She delivered a healthy baby.At the s ame time,a radical hysterectomy,omentectomy,pelvic and paraaortic lym-phadenectomies and peritonectomie s were carried out.The surgical resection was complete(no macroscopic residual disease).During histologic examination,tr aces of persis-tent disease were found.The patient underwent seven postoperative courses of chemotherapy(carboplatin +pa-clitaxel regimen)after radical surgery.After 18mont hs of follow-up posttreatment,the patie nt remains in complete remission and the childs developme nt is normal.Conclu-sion.Chemotherapy during pregnancywith preservation of the fetus could be considered and should be discussed in case of epithelial ovarian cancer(EOC)diagnosed during the second trimester of the pregnancy. Background.To report a case of succe ssful management of a FIGO stage III endometrioid carcin oma of the ovary di-agnosed during pregnancy at 22 weeks of gestation and treated with initial chemotherapy w hile preserving the pregnancy. Case. The patient underwent a planned ce -sarean section at 34 weeks after two c ourses of carboplatin. delivered a healthy baby. At the time a radical hysterectomy, omentectomy, pelvic and paraaortic lym-phadenectomies and peritonectomie s were carried out. The surgical resection was complete (no macroscopic residual disease). Turing histologic examination, trces of persis-tent disease were. The patient underwent seven postoperative courses of chemotherapy (carboplatin + pa-clitaxel regimen) after radical surgery. After 18mont hs of follow-up posttreatment, the patie nt remains in complete remission and the child’s developme nt is normal.Conclu-sion. Chemotherapy during pregnancy with preservation of the fetus could be considered and should be discussed in case of epithelial ovarian cancer (EOC) diagnosed during the second trimester of the pregnancy.
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