合欢属植物 Albizia inopinata(Harms)G.P.Lewis 广泛分布于巴西,初步药理实验证明其具有中枢神经系统(CNS)抑制作用。据此作者研究了该植物叶的总生物碱提取部位(FLA)对 CNS 的抑制作用。该植物干叶粉碎后用70%乙醇渗漉,减压除去溶剂,剩余物用常规酸碱处理得FLA。FLA 由3种大环精胺类生物碱组成。作者采用 Swiss 小鼠研究了 FLA 对活动能 Albizia inopinata (Harms) G.P. Lewis is widely distributed in Brazil and preliminary pharmacological experiments have demonstrated its central nervous system (CNS) inhibition. Based on this, the authors studied the inhibitory effect of the total alkaloid extraction fraction (FLA) of the plant leaf on CNS. The dried leaves of the plant were crushed and then percolated with 70% ethanol. The solvent was removed under reduced pressure and the residue was treated with conventional acid and alkali to obtain FLA. FLA consists of three macrocyclic spermine alkaloids. The authors used Swiss mice to study FLA activity energy