目的　探讨橄榄桥脑小脑萎缩 ( OPCA)患者的智能障碍与年龄、性别、病程、受教育程度、影像学改变及运动障碍的相关性。方法　对 38例 OPCA患者按 Hoehn和 Yahr分类标准进行分期 ;采用 HDS进行智能评价 ;用 MRI定性和线性测量方法了解 OPCA患者影像学改变 ,并与临床改变和正常对照组进行比较。对其中 2 8例进行了随访。结果　有智能障碍 1 8例 ( 4 7.4 % ) ;随年龄增长发生智能障碍的危险性增大 ;与性别和病程无相关性 ;受教育多者发生率较低 ;头影像学检查发生额颞叶萎缩。结论　本组约近一半患者发生智能障碍 ;脑的额颞叶萎缩是主要原因之一。随访发现其智能障碍与病变的部位、程度、年龄增大和运动障碍可能有关与病程长短可能不相关 Objective To investigate the relationship between mental retardation and age, sex, course of disease, education level, radiological changes and dyskinesia in olive pontine cerebellar atrophy (OPCA) patients. Methods Thirty-eight patients with OPCA underwent Hoehn and Yahr classification. The HDS was used for intelligence evaluation. The MRI findings of the patients with OPCA were compared with those of normal controls and normal controls. 28 of them were followed up. RESULTS: There were 18 cases of mental retardation (7.4%); the risk of mental retardation increased with age; there was no correlation with gender and course of disease; the incidence of more education was lower; the amount of head temporal lobe Shrinkage. Conclusions About half of the patients in this group developed mental retardation; the frontal lobe atrophy of the brain is one of the major causes. Follow-up found that their mental retardation and lesion location, degree, age and movement disorders may be related to the duration may not be related