谷氨酰胺是血中最丰富的氨基酸，缺乏后可导致肠粘膜萎缩，小肠粘膜是处于细胞增殖和细胞凋亡的平衡之中，已知肠上皮细胞的分裂素诱发性增殖需要谷氨酰胺，但不了解谷氨酸胺如何调节肠上皮细胞凋亡。作者以往的研究已证实谷氨酸胺缺乏导致肠粘膜细胞数减少，而因细胞凋亡引起 Glutamine is the most abundant amino acids in the blood, the lack of lead to mucosal atrophy, the small intestine mucosa is in the balance between cell proliferation and apoptosis, mitogen-induced proliferation of the known intestinal epithelial cells need glutamine, But do not understand how glutamate regulates intestinal epithelial cell apoptosis. Previous studies by the authors have shown that lack of glutamine leads to a decrease in the number of intestinal mucosa, which is caused by apoptosis