目前 ,骨转移癌在临床上日益多见 ,尤以肺癌、乳腺癌最为常见。疼痛、功能障碍和高钙血症是其影响患者生活质量乃至生命的主要原因。国外报道 ,大约40 %～ 5 0 %的癌性疼痛系因骨转移所致 ,其主要症状为难以控制的进行性骨痛 [1 ]。我们于 1998年 1月— 1999年 6月应用深圳海王 At present, bone metastases are increasingly seen clinically, especially in lung cancer and breast cancer. Pain, dysfunction and hypercalcaemia are the main factors that affect their quality of life and their lives. Foreign reports, about 40% ~ 50% of cancerous pain due to bone metastases, the main symptoms are difficult to control the progressive pain [1]. We applied Shenzhen Neptune from January 1998 to June 1999