The gravity inversion is to restore genetic density distribution of the underground target to be explored for explaining the internal structure and distribution of the Earth.In this paper,we propose a new 3D gravity inversion method based on 3D U-Net++.Compared with two-dimensional gravity inversion,three-dimensional(3D)gravity inversion can more precisely describe the density distribution of underground space.However,conventional 3D gravity inversion method input is two-dimensional,the input and output of the network proposed in our method are three-dimensional.In the training stage,we design a large number of diversified simulation model-data pairs by using the random walk method to improve the generalization ability of the network.In the test phase,we verify the network performance by using the model-data pairs generated by the simulation.To further illustrate the effectiveness of the algorithm,we apply the method to the inversion of the San Nicolas mining area,and the inversion results are basically consistent with the borehole measurement results.Moreover,the results of the 3D U-Net++inversion and the 3D U-Net inversion are compared.The density models of the 3D U-Net++inversion have higher resolution,more concentrated inversion results,and a clearer boundary of the density model.