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目的对比研究单独使用伊木萨克片或帕罗西汀的治疗方案以及两种药物联合使用的治疗方案治疗早泄(PE)的临床效果。方法 136例患者,分为伊木萨克片组39例,帕罗西汀组47例,联合组50例,分别以口服伊木萨克片3片/d,帕罗西汀20 mg/d,联合使用两种药物治疗早泄,疗程均为30 d,对比三种治疗方案的患者在治疗前后的阴道内射精潜伏时间(IELT)和性伴侣满意程度评分结果,同时统计各治疗方案的副作用。结果各方案治疗后的IELT明显提高,其中以联合组最为明显,而治疗后性伴侣满意度评分差异无统计学意义(P>0.05)。三种治疗方案以联合组治愈率为最高,达到82.0%。差异有统计学意义(P<0.05),结论联合使用伊木萨克片、帕罗西汀治疗PE有较高的治愈率,能明显提高患者的IELT和其性伴侣的满意程度,可予以临床推广。
Objective To compare the clinical effects of the treatment regimen of using the moxibustion alone or paroxetine alone and the combination of two drugs in the treatment of premature ejaculation (PE). Methods Thirty-six patients were divided into two groups: 39 cases in the moxibustion group, 47 cases in the paroxetine group, and 50 cases in the combination group. They were given omeprazole tablet 3 tablets / day and paroxetine 20 mg / day respectively, Premature ejaculation was treated for 30 days. The intravaginal ejaculation latency (IELT) and sexual satisfaction scores were compared between the three treatment regimens. The side effects of each treatment regimen were also calculated. Results After treatment, the IELT was significantly increased, especially in the combined group, but there was no significant difference in the satisfaction scores of sexual partners after treatment (P> 0.05). The three treatment regimens in the combined group the highest cure rate, reaching 82.0%. (P <0.05). Conclusions The combination of moxibustion and paroxetine in the treatment of PE has a higher cure rate, which can significantly improve the IELT and sexual partners’ satisfaction, which may be clinically promoted.