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氟乙酰胺又名敌牙胺,为我国禁止使用的剧毒物,但仍有少数不法分子在生产和销售以其为原料的鼠药,以及早期购买,未及处理的鼠药,因其适口性好,且包装类似食品易被儿童误服,造成严重中毒甚至危及生命。近年来有关此类报道较多,但谈及具体治疗较少,尤其是小儿洗胃时每次的量和总量及质均无具体报道。现我们将18例急性氟乙酰胺中毒抢救体会总结如下。1 临床资料 18例均来自农村。其中男12例,女6例,年龄1.5-6岁,均有明确的直接口服毒物史,服后发病时间在15min-5h。主要临床表现:神志模糊17例,其中昏迷8例,抽搐15例;呕吐16例。实验室检查:白细胞总数正常或轻度升高(WBC>14.0×10~9/L)12例,较高(WBC>20.0×10~9/L)4例;心肌酶谱(CK.CK-MB.LDH.HBDH,AST)有不同程度增高11例,其中以CK(341-6520u/L均值2016U/L)增高最明显;肝功能异常5例;肾功能异常2例;心电图异常3例,电解质异常5例。
Fluoroacetamide, also known as aides and amines, is a highly toxic toxin banned in China. However, there are still a few lawbreakers who manufacture and sell rat drugs that are used as raw materials, Good sex, and packing similar foods easily mistaken children, causing serious poisoning and even life-threatening. In recent years, there are more reports on such reports, but fewer specific treatments are mentioned, especially when pediatric gastric lavage is not reported in any quantity, quantity and quality. Now we will 18 cases of acute fluoroacetamide rescue experience summarized as follows. 1 clinical data 18 cases were from rural areas. Including 12 males and 6 females, aged 1.5-6 years old, have a clear history of direct oral poisoning, the onset time after serving in 15min-5h. The main clinical manifestations: 17 cases of ambiguity, of which 8 cases of coma, convulsions in 15 cases; vomiting in 16 cases. There were 12 cases with normal or mild leukocyte count (WBC> 14.0 × 10 ~ 9 / L) and 4 cases with high (WBC> 20.0 × 10 ~ 9 / L) MB.LDH.HBDH, AST) increased to some extent in 11 cases, of which CK (341-6520u / L means 2016U / L) increased most obviously; 5 cases of liver dysfunction; 2 cases of renal dysfunction; 3 cases of abnormal electrocardiogram, Electrolyte abnormalities in 5 cases.